LbrM.35.4690

mitochondrial intermediate peptidase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102110 OG7: OG7_0002961 99 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 99 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.33.2790 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
LbrM.35.4140 ⚠
S-adenosylhomocysteine hydrolase
— OG7
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LbrM.02.0040 ⚠
aminopeptidase P1, putative, metallo-peptidas
— OG7
LbrM.04.0010 ⚠
phosphoacetylglucosamine mutase-like gene
— OG7
LbrM.24.2140 ⚠
transketolase
— OG7
LbrM.15.0910 ⚠
myo-inositol-1 phosphatase, putative
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.15.1140 ⚠
protein kinase, putative
— OG7
LbrM.20.3180 ⚠
adenosine kinase-like protein
— OG7
LbrM.33.2590 ⚠
udp-glc 4'-epimerase, putative
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.35.2580 ⚠
tyrosine aminotransferase
— OG7
LbrM.04.0630 ⚠
spermidine synthase, putative
— OG7
LbrM.22.1510 ⚠
ser/thr protein phosphatase, putative
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.06.1050 ⚠
deoxyribose-phosphate aldolase, putative
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.35.6930 ⚠
hypothetical protein, conserved, y113g7b.23 p
— OG7
LbrM.07.0190 ⚠
protein phosphatase 2A, regulatory subunit B,
— OG7
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.17.0570 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG7
LbrM.13.0500 ⚠
Metallopeptidase family M24, putative
— OG7
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0930 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.29.1660 ⚠
metallo-peptidase, Clan MH, Family M18, gluta
— OG7
LbrM.09.0850 ⚠
oligopeptidase b
— OG7
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— OG7
LbrM.22.0480 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LbrM.33.2430 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1010 ⚠
adenosine kinase, putative
— OG7
LbrM.35.4150 ⚠
S-adenosylhomocysteine hydrolase
— OG7
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— OG7
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— OG7
LbrM.16.0560 ⚠
aspartate carbamoyltransferase, putative
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.25.2020 ⚠
Xaa-Pro aminopeptidase, putative
— OG7
LbrM.27.1560 ⚠
choline kinase, ethanolamine kinase, putative
— OG7
LbrM.27.0930 ⚠
WD domain, G-beta repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.