LbrM.04.0630

spermidine synthase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100634 OG7: OG7_0003460 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— Both
LbrM.20.0030 ⚠
malate dehydrogenase
— Both
LbrM.20.1430 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LbrM.35.7010
2,3-bisphosphoglycerate-independent phosphogl
— Both
LbrM.28.2170
ribose 5-phosphate isomerase, putative
— Both
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— Both
LbrM.35.3820 ⚠
cysteine synthase
— OG6
LbrM.01.0520 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LbrM.14.1300 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
LbrM.14.0350
threonine synthase, putative
— Both
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.27.2210
branched-chain amino acid aminotransferase, p
— Both
LbrM.01.0540 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LbrM.01.0550 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— Both
LbrM.27.2780 ⚠
metallo-peptidase, Clan MA(E), Family M3
— Both
LbrM.01.0560 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LbrM.01.0260 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.29.0500 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.0500 ⚠
Metallopeptidase family M24, putative
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.22.1510 ⚠
ser/thr protein phosphatase, putative
— OG7
LbrM.33.3140 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
LbrM.33.3110 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.35.4690 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LbrM.17.0570 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— Both
LbrM.27.2010 ⚠
trypanothione synthetase
— Both
LbrM.32.1050
ubiquitin-conjugating enzyme protein, putativ
— Both
LbrM.26.0640
hypothetical protein, conserved
— Both
LbrM.20.1010 ⚠
uracil phosphoribosyltransferase, putative
— Both
LbrM.31.2760 ⚠
uridine kinase-like protein
— Both
LbrM.31.2810 ⚠
uridine kinase-like protein
— Both
LbrM.29.2850
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LbrM.06.0570
dUTP diphosphatase, deoxyuridine triphosphata
— Both
LbrM.28.3070
cytosolic malate dehydrogenase
— Both
LbrM.19.0470 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LbrM.15.0550 ⚠
ecotin, putative
— Both
LbrM.06.0640
protein kinase, putative
— OG6
LbrM.25.1930
AGC essential kinase 1
— OG6
LbrM.22.0480 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— Both
LbrM.03.0240 ⚠
long chain fatty Acyl CoA synthetase, putativ
— Both
LbrM.06.1050
deoxyribose-phosphate aldolase, putative
— Both
LbrM.33.2790
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.