LbrM.28.3070

cytosolic malate dehydrogenase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101066 OG7: OG7_0004490 26 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 26 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.24.2140
transketolase
— Both
LbrM.29.1660 ⚠
metallo-peptidase, Clan MH, Family M18, gluta
— OG7
LbrM.33.3110 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
LbrM.33.3140 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.35.7010
2,3-bisphosphoglycerate-independent phosphogl
— Both
LbrM.07.0280 ⚠
acetylornithine deacetylase-like protein
— Both
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— Both
LbrM.35.3820 ⚠
cysteine synthase
— OG6
LbrM.18.0510
serine carboxypeptidase (CBP1), putative, ser
— Both
LbrM.27.2010 ⚠
trypanothione synthetase
— Both
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— Both
LbrM.20.0030 ⚠
malate dehydrogenase
— Both
LbrM.30.1370
pyridoxal kinase, putative
— Both
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.14.0350
threonine synthase, putative
— Both
LbrM.27.2210
branched-chain amino acid aminotransferase, p
— Both
LbrM.04.0630
spermidine synthase, putative
— Both
LbrM.29.2850
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LbrM.26.0840
aspartate--ammonia ligase, putative, asparagi
— Both
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.06.0570
dUTP diphosphatase, deoxyuridine triphosphata
— Both
LbrM.10.1110
nucleoside phosphorylase-like protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.