LbrM.20.0020

malate dehydrogenase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_192279 OG7: OG7_0004751 66 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 66 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.04.0630 ⚠
spermidine synthase, putative
— OG7
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG7
LbrM.02.0670 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG7
LbrM.26.1590 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG7
LbrM.27.1650 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG7
LbrM.35.4690 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LbrM.13.0500 ⚠
Metallopeptidase family M24, putative
— OG7
LbrM.19.0470 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LbrM.05.0350 ⚠
trypanothione reductase
— OG7
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG7
LbrM.27.2780 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LbrM.31.1330 ⚠
amidohydrolase, putative
— OG7
LbrM.14.0960 ⚠
sodium/hydrogen exchanger, putative
— OG7
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LbrM.09.0850 ⚠
oligopeptidase b
— OG7
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— OG7
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.22.0480 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.29.0500 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.15.0550 ⚠
ecotin, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.35.6930 ⚠
hypothetical protein, conserved, y113g7b.23 p
— OG7
LbrM.22.1510 ⚠
ser/thr protein phosphatase, putative
— OG7
LbrM.17.0570 ⚠
bis(5'-nucleosyl)-tetraphosphatase, symmetric
— OG7
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.33.2790 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.30.1050 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.35.2240 ⚠
chaperonin HSP60, mitochondrial precursor
— OG7
LbrM.27.2010 ⚠
trypanothione synthetase
— OG7
LbrM.27.0810 ⚠
reductase, putative
— OG7
LbrM.35.3170 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— OG7
LbrM.32.2570 ⚠
cytochrome-b5 reductase, putative
— OG7
LbrM.13.0880 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LbrM.22.0710 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LbrM.23.1970 ⚠
cytochrome c oxidase subunit V
— OG7
LbrM.14.0350 ⚠
threonine synthase, putative
— OG7
LbrM.19.0050 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LbrM.20.5360 ⚠
triosephosphate isomerase
— OG7
LbrM.22.0720 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LbrM.34.3350 ⚠
replication factor A protein 3, putative
— OG7
LbrM.26.0130 ⚠
adenine phosphoribosyltransferase
— OG7
LbrM.30.1370 ⚠
pyridoxal kinase, putative
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
Page 1 of 2
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.