LbrM.14.0960

sodium/hydrogen exchanger, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_103025 OG7: OG7_0006471 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.05.0350
trypanothione reductase
— Both
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.3080 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— Both
LbrM.20.0030 ⚠
malate dehydrogenase
— Both
LbrM.09.0850 ⚠
oligopeptidase b
— Both
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— Both
LbrM.20.2170 ⚠
ruvB-like DNA helicase, putative
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.15.1440
proliferative cell nuclear antigen (PCNA), pu
— Both
LbrM.31.3520 ⚠
metallo-peptidase, Clan ME, Family M16
— Both
LbrM.31.3470 ⚠
metallopeptidase, putative
— Both
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— Both
LbrM.30.1050 ⚠
hypothetical protein, conserved
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.