LbrM.05.0350

trypanothione reductase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101659 OG7: OG7_0001626 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.14.0960
sodium/hydrogen exchanger, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.33.2430 ⚠
hypothetical protein, conserved
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.20.2170 ⚠
ruvB-like DNA helicase, putative
— Both
LbrM.35.0120 ⚠
stress-inducible protein STI1 homolog
— OG6
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.20.0030 ⚠
malate dehydrogenase
— Both
LbrM.09.0850 ⚠
oligopeptidase b
— Both
LbrM.20.4800
cytidine triphosphate synthase, putative, CTP
— Both
LbrM.20.3080 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LbrM.20.0040 ⚠
malate dehydrogenase, putative
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.30.3450 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.35.5830 ⚠
aminopeptidase P1, putative, metallo-peptidas
— OG7
LbrM.30.3180
3-hydroxy-3-methylglutaryl-CoA reductase, put
— Both
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— Both
LbrM.29.0910
guanine deaminase, putative
— Both
LbrM.29.2220 ⚠
Aminopeptidase M1, putative
— Both
LbrM.23.0300
pteridine reductase 1
— Both
LbrM.29.1930 ⚠
Fumarate hydratase class I, cytosolic
— Both
LbrM.05.0800
methylthioadenosine phosphorylase, putative
— Both
LbrM.14.1330 ⚠
enolase
— Both
LbrM.30.3550
S-adenosylmethionine synthetase
— Both
LbrM.32.3210 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.33.1600
glutamine aminotransferase, putative
— Both
LbrM.30.1050 ⚠
hypothetical protein, conserved
— Both
LbrM.26.2160
kynureninase, putative
— Both
LbrM.14.1320 ⚠
enolase
— Both
LbrM.34.3250
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LbrM.24.0320 ⚠
fumarate hydratase, putative
— Both
LbrM.32.3200 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.34.2300 ⚠
metallo-peptidase, Clan MG, Family M24, amino
— Both
LbrM.34.2990
glycerol kinase, glycosomal, putative
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.