LbrM.30.1491

N-acyl-L-amino acid amidohydrolase, putative

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101553 OG7: OG7_0005942 186 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 186 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.11.0400 ⚠ aminopeptidase, putative, metallo-peptidase,	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LbrM.11.0410 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LbrM.33.2840 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LbrM.35.5900 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LbrM.04.0360 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	OG7
LbrM.28.0340 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_280470.1 OG6 LdBPK_201740.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 +1 more	Both
LbrM.28.0460 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	Both
LbrM.20.0010 ⚠ mitochondrial malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LbrM.34.5160 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LbrM.26.1390 ⚠ GTP-binding protein-like protein, guanine nuc	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LbrM.24.1810 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.35.7140 ⚠ hypothetical protein	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.27.0170 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.06.0980 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.23.0880 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.33.0500 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.20.1020 ⚠ TPR repeat/SET domain containing protein, put	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.23.0910 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.20.6030 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LbrM.20.3080 ⚠ ruvb-like 1 DNA helicase, putative	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	OG7
LbrM.17.0610 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LbrM.20.2160 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LbrM.17.0630 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LbrM.29.2030 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_201720.1 OG7 LdBPK_130530.1 ↔ LdBPK_201740.1	OG7
LbrM.33.1320 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_008414	Both
LbrM.20.6130 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_200770.1 ↔ LdBPK_201720.1 OG6 LdBPK_200770.1 ↔ LdBPK_201740.1 OG7 LdBPK_200770.1 ↔ LdBPK_201720.1 OG7 LdBPK_200770.1 ↔ LdBPK_201740.1	Both
LbrM.12.0300 ⚠ ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_201720.1 OG6 LdBPK_120105.1 ↔ LdBPK_201740.1 OG7 LdBPK_120105.1 ↔ LdBPK_201720.1 OG7 LdBPK_120105.1 ↔ LdBPK_201740.1	Both
LbrM.20.4940 ⚠ conserved protein, unknown function	—	OG6 LdBPK_200770.1 ↔ LdBPK_201720.1 OG6 LdBPK_200770.1 ↔ LdBPK_201740.1 OG7 LdBPK_200770.1 ↔ LdBPK_201720.1 OG7 LdBPK_200770.1 ↔ LdBPK_201740.1	Both
LbrM.27.2230 ⚠ ribonucleoside-diphosphate reductase small ch	—	OG6 LdBPK_201720.1 ↔ LdBPK_221110.1 OG6 LdBPK_201740.1 ↔ LdBPK_221110.1 OG7 LdBPK_201720.1 ↔ LdBPK_221110.1 OG7 LdBPK_201740.1 ↔ LdBPK_221110.1	Both
LbrM.24.1960 ⚠ cyclin 10	—	OG6 LdBPK_201720.1 ↔ LdBPK_241960.1 OG6 LdBPK_201740.1 ↔ LdBPK_241960.1 OG7 LdBPK_201720.1 ↔ LdBPK_241960.1 OG7 LdBPK_201740.1 ↔ LdBPK_241960.1	Both
LbrM.34.1120 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LbrM.33.2550 ⚠ glycosyl hydrolase-like protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_332390.1 OG6 LdBPK_201740.1 ↔ LdBPK_332390.1 OG7 LdBPK_201720.1 ↔ LdBPK_332390.1 OG7 LdBPK_201740.1 ↔ LdBPK_332390.1	Both
LbrM.31.1330 ⚠ amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LbrM.30.3060 ⚠ tRNA (Guanine-1)-methyltransferase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_303110.1 OG6 LdBPK_201740.1 ↔ LdBPK_303110.1 OG7 LdBPK_201720.1 ↔ LdBPK_303110.1 OG7 LdBPK_201740.1 ↔ LdBPK_303110.1	Both
LbrM.27.1820 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_271580.1 OG6 LdBPK_201740.1 ↔ LdBPK_271580.1 OG7 LdBPK_201720.1 ↔ LdBPK_271580.1 OG7 LdBPK_201740.1 ↔ LdBPK_271580.1	Both
LbrM.34.4530 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LbrM.30.1590 ⚠ phosphopantothenoylcysteine decarboxylase, pu	—	OG6 LdBPK_201720.1 ↔ LdBPK_301550.1 OG6 LdBPK_201740.1 ↔ LdBPK_301550.1 OG7 LdBPK_201720.1 ↔ LdBPK_301550.1 OG7 LdBPK_201740.1 ↔ LdBPK_301550.1	Both
LbrM.26.1240 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_261200.1 OG6 LdBPK_201740.1 ↔ LdBPK_261200.1 OG7 LdBPK_201720.1 ↔ LdBPK_261200.1 OG7 LdBPK_201740.1 ↔ LdBPK_261200.1	Both
LbrM.25.0920 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_251070.1 OG6 LdBPK_201740.1 ↔ LdBPK_251070.1 OG7 LdBPK_201720.1 ↔ LdBPK_251070.1 OG7 LdBPK_201740.1 ↔ LdBPK_251070.1	Both
LbrM.19.0530 ⚠ polyprenyl synthase, putative	—	OG6 LdBPK_190210.1 ↔ LdBPK_201720.1 OG6 LdBPK_190210.1 ↔ LdBPK_201740.1 OG7 LdBPK_190210.1 ↔ LdBPK_201720.1 OG7 LdBPK_190210.1 ↔ LdBPK_201740.1	Both
LbrM.05.0470 ⚠ GTPase, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LbrM.20.0030 ⚠ malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LbrM.30.0540 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
LbrM.21.1130 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	Both
LbrM.35.4280 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_008197 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_008197 ↔ TCSYLVIO_008414	Both
LbrM.33.2190 ⚠ ribosome assembly protein RRB1, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_332020.1 OG6 LdBPK_201740.1 ↔ LdBPK_332020.1 OG7 LdBPK_201720.1 ↔ LdBPK_332020.1 OG7 LdBPK_201740.1 ↔ LdBPK_332020.1	Both
LbrM.30.0550 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_300480.1 OG6 LdBPK_201740.1 ↔ LdBPK_300480.1 OG7 LdBPK_201720.1 ↔ LdBPK_300480.1 OG7 LdBPK_201740.1 ↔ LdBPK_300480.1	Both
LbrM.34.4150 ⚠ hsp70 subfamily B suppressor 1, elongation fa	—	OG6 LdBPK_201720.1 ↔ LdBPK_354220.1 OG6 LdBPK_201740.1 ↔ LdBPK_354220.1 OG7 LdBPK_201720.1 ↔ LdBPK_354220.1 OG7 LdBPK_201740.1 ↔ LdBPK_354220.1	Both
LbrM.30.0820 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_008414	Both
LbrM.34.2220 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_352320.1 OG6 LdBPK_201740.1 ↔ LdBPK_352320.1	OG6

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