LbrM.33.2840

metallo-peptidase, Clan MF, Family M17
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_105603 OG7: OG7_0003405 276 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 276 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.31.1330 ⚠
amidohydrolase, putative
— +7 more Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— +7 more Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— +7 more Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— +7 more Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— +7 more Both
LbrM.30.0880 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.35.4280 ⚠
hypothetical protein, conserved
— +2 more Both
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— +1 more Both
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— +1 more Both
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— +1 more Both
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.18.1310 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LbrM.31.0410 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.05.0890 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.24.1950 ⚠
cyclin 11, putative
— OG7
LbrM.29.2330 ⚠
aspartyl aminopeptidase, putative
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.15.0400 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.35.1510 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1800 ⚠
microtubule associated protein xmap215
— OG7
LbrM.29.1790 ⚠
MORN repeat, putative
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0730 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LbrM.32.0910 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.35.1470 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3910 ⚠
nucleolar protein family a, putative
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.07.0840 ⚠
6-phosphofructo-2-kinase-like protein
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.