LbrM.29.2330

aspartyl aminopeptidase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102047 OG7: OG7_0006128 216 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 216 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LbrM.03.0880 ⚠
MORN repeat, putative
— OG7
LbrM.29.1830 ⚠
paraflagellar rod protein 1D, putative
— OG7
LbrM.27.1990 ⚠
paraflagellar rod protein 5, putative
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.17.1250 ⚠
WW domain containing protein, putative
— OG7
LbrM.32.1490 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.13.1120 ⚠
AAA domain/Dpy-30 motif containing protein, p
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.13.0070 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.02.0360
Soluble NSF attachment protein, SNAP, putativ
— Both
LbrM.07.0610
hypothetical protein, conserved
— Both
LbrM.33.0830
ATP synthase F1 subunit gamma protein
— Both
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.09.1000
O-phosphoseryl-tRNA(Sec) selenium transferase
— Both
LbrM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— Both
LbrM.07.0990
Domain of unknown function (DUF3437), putativ
— Both
LbrM.11.0720
Short C-terminal domain/PUB domain containing
— Both
LbrM.22.0060 ⚠
transcription factor-like protein
— Both
LbrM.11.0690
hypothetical protein, conserved
— Both
LbrM.27.2110 ⚠
hypothetical protein, conserved
— Both
LbrM.12.0530 ⚠
WW domain containing protein, putative
— Both
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.06.0800
lipin, putative
— Both
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.18.1100
5-oxoprolinase, putative
— Both
LbrM.24.0500
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LbrM.26.0030
brix domain containing-like protein
— Both
LbrM.35.0740
hypothetical protein, conserved
— Both
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.