LbrM.11.0720

Short C-terminal domain/PUB domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147134 OG7: OG7_0042684 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.11.0730
hypothetical protein, conserved
— Both
LbrM.30.0640
hypothetical protein, conserved
— Both
LbrM.33.2150
hypothetical protein, conserved
— Both
LbrM.28.2080
p21-C-terminal region-binding protein, putati
— Both
LbrM.26.1240 ⚠
hypothetical protein, conserved
— Both
LbrM.26.1490 ⚠
farnesyltransferase beta subunit
— Both
LbrM.32.1140
hypothetical protein, conserved
— Both
LbrM.12.0530 ⚠
WW domain containing protein, putative
— Both
LbrM.13.0440
hypothetical protein, conserved
— Both
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.34.1630
casein kinase II, putative
— OG6
LbrM.11.0690
hypothetical protein, conserved
— Both
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.02.0360
Soluble NSF attachment protein, SNAP, putativ
— Both
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.32.0820 ⚠
Outer row dynein-assembly protein 7
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.17.1250 ⚠
WW domain containing protein, putative
— OG7
LbrM.28.2700 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.31.0420 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— OG7
LbrM.31.0480 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.