LbrM.26.1440

FYVE zinc finger, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_150730 OG7: OG7_0001169 243 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 243 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.11.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— Both
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.30.1800 ⚠
microtubule associated protein xmap215
— OG7
LbrM.35.1510 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.35.2690 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1470 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.3110 ⚠
RNA-binding protein, putative
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.33.2430 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3450 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.16.0030 ⚠
AAA domain containing protein, putative
— OG7
LbrM.04.0960 ⚠
adenylate kinase, putative
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LbrM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LbrM.16.1550 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.4740 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LbrM.29.2330 ⚠
aspartyl aminopeptidase, putative
— OG7
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LbrM.32.1490 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.35.3060 ⚠
Flagellar Member 2
— OG7
LbrM.13.0730 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.1960 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— OG7
LbrM.10.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.1300 ⚠
Gamma-soluble NSF attachment protein (SNAP-ga
— OG7
LbrM.33.2150 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.2370 ⚠
cullin-like protein-like protein
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.7000 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4260 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.