LbrM.34.4260

Spindle assembly abnormal protein 6 homolog
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_104016 OG7: OG7_0006650 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.6500 ⚠
Sucrase/ferredoxin-like, putative
— Both
LbrM.35.4110 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LbrM.33.1160 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LbrM.32.2000 ⚠
iron superoxide dismutase, putative
— OG7
LbrM.08.0330 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
LbrM.12.0030 ⚠
PITH domain-containing protein
— OG7
LbrM.05.0310 ⚠
monothiol glutaredoxin, putative
— OG7
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— OG7
LbrM.34.1170 ⚠
thioredoxin-like protein
— OG7
LbrM.01.0140 ⚠
monothiol glutaredoxin, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.35.4740 ⚠
Protein of unknown function (DUF2870), putati
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.32.2860 ⚠
superoxide dismutase, putative
— OG7
LbrM.32.2010 ⚠
iron superoxide dismutase, putative
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.2630 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— OG7
LbrM.16.1550 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LbrM.30.3450 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2430 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.0050 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
LbrM.32.1200 ⚠
exportin 1, putative
— OG7
LbrM.26.0350 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.1110 ⚠
hypothetical protein, conserved
— Both
LbrM.08.0050 ⚠
hypothetical protein, unknown function
— Both
LbrM.25.2260 ⚠
hypothetical protein, conserved
— Both
LbrM.22.0930 ⚠
hypothetical protein, conserved
— Both
LbrM.25.2210 ⚠
hypothetical protein SCD6.10
— Both
LbrM.20.0460 ⚠
calcium channel protein, putative, ion transp
— Both
LbrM.28.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.3400 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LbrM.27.1970 ⚠
GTP binding protein, putative
— OG7
LbrM.27.2520 ⚠
GTP binding protein, putative
— OG7
LbrM.28.1760 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.1300 ⚠
Gamma-soluble NSF attachment protein (SNAP-ga
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.21.0560 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1360 ⚠
Serine-threonine kinase receptor-associated p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.