LbrM.05.0310

monothiol glutaredoxin, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101660 OG7: OG7_0003454 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.1550 ⚠
hypothetical protein, conserved
— Both
LbrM.29.1510 ⚠
RNA binding protein, putative
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.29.2920 ⚠
RNA binding protein, putative
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.18.1200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.18.0200 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LbrM.26.2030 ⚠
protein kinase, putative
— OG7
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.34.4260 ⚠
Spindle assembly abnormal protein 6 homolog
— OG7
LbrM.27.1970 ⚠
GTP binding protein, putative
— OG7
LbrM.32.3400 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.35.4110 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LbrM.31.2910 ⚠
hypothetical protein, unknown function
— OG7
LbrM.35.4740 ⚠
Protein of unknown function (DUF2870), putati
— Both
LbrM.33.2430 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.3790 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.1440 ⚠
RNA-binding protein, putative
— OG7
LbrM.02.0420 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
LbrM.22.1160 ⚠
hypothetical protein, unknown function
— OG7
LbrM.25.0470 ⚠
RNA-binding protein, putative
— OG7
LbrM.34.2571 ⚠
ankyrin repeat protein, putative
— OG7
LbrM.35.1350 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.18.0190 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LbrM.20.1190 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
LbrM.18.0210 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.35.6800 ⚠
hypothetical protein, unknown function
— OG7
LbrM.17.0340 ⚠
cytidine deaminase-like protein
— OG7
LbrM.08.0330 ⚠
iron superoxide dismutase A, mitochondrial
— Both
LbrM.35.7000 ⚠
hypothetical protein, conserved
— Both
LbrM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
LbrM.22.1430 ⚠
dephospho-CoA kinase, putative
— OG6
LbrM.21.0560 ⚠
hypothetical protein, conserved
— Both
LbrM.30.3450 ⚠
hypothetical protein, conserved
— Both
LbrM.26.0350 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
LbrM.30.2550 ⚠
formate--tetrahydrofolate ligase
— OG6
LbrM.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.04.0120 ⚠
hypothetical protein, conserved
— Both
LbrM.32.2000 ⚠
iron superoxide dismutase, putative
— Both
LbrM.32.2010 ⚠
iron superoxide dismutase, putative
— Both
LbrM.32.2860 ⚠
superoxide dismutase, putative
— Both
LbrM.23.0170 ⚠
hypothetical protein, conserved
— OG6
LbrM.32.2870 ⚠
superoxide dismutase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.