LbrM.10.0200

Mitogen-activated protein kinase 10, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147455 OG7: OG7_0000396 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.3380
phosphomannomutase-like protein
— OG6
LbrM.32.3920
enoyl-CoA hydratase/isomerase family protein,
— OG6
LbrM.18.0030
mevalonate-diphosphate decarboxylase, putativ
— OG6
LbrM.31.1280
biotin/lipoate protein ligase-like protein
— OG6
LbrM.33.0090
hypothetical protein, conserved
— OG6
LbrM.07.0960 ⚠
protein kinase, putative, serine/threonine ki
— OG6
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— OG6
LbrM.29.0280
UBX domain-containing protein
— OG6
LbrM.18.0230
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LbrM.30.2560
RNA-binding protein, putative
— OG6
LbrM.28.1520
haloacid dehalogenase-like hydrolase, putativ
— OG6
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— OG6
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— OG6
LbrM.29.1390
carnitine/choline acetyltransferase, putative
— OG6
LbrM.32.1200
exportin 1, putative
— OG6
LbrM.25.1580
hypothetical protein, conserved
— OG6
LbrM.32.1000
Alpha/beta hydrolase family, putative
— OG6
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG6
LbrM.28.1190
WD domain, G-beta repeat, putative
— OG6
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— OG6
LbrM.27.2520
GTP binding protein, putative
— OG6
LbrM.35.4230
ATP-dependent protease subunit HslV, putative
— OG6
LbrM.27.2510 ⚠
protein phosphatase-like protein
— OG6
LbrM.30.0420
phosphatase 2C, putative
— OG6
LbrM.35.0620 ⚠
protein phosphatase 2C-like protein
— OG6
LbrM.30.0990 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
LbrM.28.1220
electron-transfer-flavoprotein, alpha polypep
— OG6
LbrM.23.1720
alanine racemase, putative
— OG6
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.22.0310
SEP domain containing protein, putative
— OG6
LbrM.16.0050
2OG-Fe(II) oxygenase superfamily, putative
— OG6
LbrM.28.0070
hypothetical protein, conserved
— OG6
LbrM.12.0030
PITH domain-containing protein
— OG6
LbrM.18.1050
UDP-glucose pyrophosphorylase
— OG6
LbrM.08.0510
hypothetical protein, conserved
— OG6
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG6
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG6
LbrM.06.1050
deoxyribose-phosphate aldolase, putative
— OG6
LbrM.27.0800
UBA/TS-N domain containing protein, putative
— OG6
LbrM.13.1300
Gamma-soluble NSF attachment protein (SNAP-ga
— OG6
LbrM.08.0330 ⚠
iron superoxide dismutase A, mitochondrial
— OG6
LbrM.32.2000 ⚠
iron superoxide dismutase, putative
— OG6
LbrM.32.2010 ⚠
iron superoxide dismutase, putative
— OG6
LbrM.32.2860 ⚠
superoxide dismutase, putative
— OG6
LbrM.32.2870 ⚠
superoxide dismutase, putative
— OG6
LbrM.33.3090
transcription elongation factor-like protein
— OG6
LbrM.28.2260
tRNA threonylcarbamoyl adenosine modification
— OG6
LbrM.35.0680
Elongation factor G1, mitochondrial, putative
— OG6
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.21.0070
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.