LbrM.18.0720

serine/threonine kinase-like protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_105113 OG7: OG7_0000009 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.5000 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.18.1050 ⚠
UDP-glucose pyrophosphorylase
— Both
LbrM.12.0030 ⚠
PITH domain-containing protein
— Both
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.28.0340 ⚠
rrp44p homologue, putative
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.20.4940 ⚠
conserved protein, unknown function
— OG7
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.15.0700 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.18.0740 ⚠
HEAT repeats, putative
— OG7
LbrM.20.6130 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.2160 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.06.0520 ⚠
U-box domain containing protein, putative
— OG7
LbrM.15.1020 ⚠
DNA repair protein Rad9, putative
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.35.3060 ⚠
Flagellar Member 2
— OG7
LbrM.17.1600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LbrM.17.1420 ⚠
Organic solute transport protein 1, putative
— OG7
LbrM.20.4450 ⚠
deoxyhypusine synthase, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.30.2810 ⚠
GTPase activator-like protein
— OG7
LbrM.20.0300 ⚠
deoxyhypusine synthase, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.32.1490 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.09.1350 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.24.0660 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.11.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.1440 ⚠
alanyl-tRNA synthetase, putative
— OG7
LbrM.32.3900 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.32.3910 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LbrM.10.1490 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.35.0650 ⚠
ubiquitin-like protein, putative
— OG7
LbrM.26.1310 ⚠
Cupin-like domain containing protein, putativ
— OG7
LbrM.13.0550 ⚠
ubiquitin-like protein
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.