LbrM.15.0700

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_104566 OG7: OG7_0002491 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.0340 ⚠
rrp44p homologue, putative
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— Both
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.06.0930
glucosamine-fructose-6-phosphate aminotransfe
— Both
LbrM.14.0880
glutathione synthetase, putative
— Both
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— Both
LbrM.18.0740
HEAT repeats, putative
— Both
LbrM.14.0420
Protein of unknown function (DUF1253), putati
— Both
LbrM.13.0460 ⚠
hypothetical protein, conserved
— Both
LbrM.14.1540
myo-inositol-1-phosphate synthase, inositol-3
— Both
LbrM.11.0970 ⚠
eukaryotic release factor 3, putative
— Both
LbrM.26.1310
Cupin-like domain containing protein, putativ
— Both
LbrM.02.0360
Soluble NSF attachment protein, SNAP, putativ
— Both
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— Both
LbrM.22.1440
alanyl-tRNA synthetase, putative
— Both
LbrM.35.3060
Flagellar Member 2
— Both
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LbrM.12.0300
ornithine decarboxylase, putative
— Both
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.07.0960 ⚠
protein kinase, putative, serine/threonine ki
— OG7
LbrM.28.2190 ⚠
protein lipid droplet kinase (LDK)
— OG7
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— OG7
LbrM.22.0750 ⚠
protein kinase, putative, serine/threonine pr
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.29.2030 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.20.2160 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.30.3660 ⚠
CYC2-like protein, putative
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.03.0070 ⚠
Met-10+ like-protein, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.