LbrM.19.1790

FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100299 OG7: OG7_0001020 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.0880 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0310 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.1010 ⚠
E1-like ubiquitin-activating enzyme, putative
— OG7
LbrM.15.1340 ⚠
arginine N-methyltransferase
— OG7
LbrM.03.0130 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.0040 ⚠
arginine N-methyltransferase, type I
— OG7
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG7
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.12.0300 ⚠
ornithine decarboxylase, putative
— OG7
LbrM.22.0060 ⚠
transcription factor-like protein
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0530 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0730 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LbrM.17.1330 ⚠
methyltransferase domain containing protein,
— OG7
LbrM.15.0400 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.26.1180 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.25.0680 ⚠
DNL zinc finger, putative
— OG7
LbrM.29.1330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.29.2130 ⚠
cdc2-related kinase 10, putative
— OG7
LbrM.32.0910 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.33.1670 ⚠
protein kinase
— OG7
LbrM.14.1240 ⚠
EAP30/Vps36 family, putative
— OG7
LbrM.35.6540 ⚠
flagellum transition zone component, putative
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.31.1630 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.19.0530 ⚠
polyprenyl synthase, putative
— OG7
LbrM.24.1950 ⚠
cyclin 11, putative
— OG7
LbrM.05.0890 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.33.0820 ⚠
G1 cyclin CycE4, putative
— OG7
LbrM.30.3660 ⚠
CYC2-like protein, putative
— OG7
LbrM.24.1960 ⚠
cyclin 10
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.17.1560 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.02.0360 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
LbrM.06.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2720 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.1140 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.