LbrM.14.1240

EAP30/Vps36 family, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102942 OG7: OG7_0008031 104 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 104 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.27.2130
small nuclear ribonucleoprotein protein, puta
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.25.0970
hypothetical protein, conserved
— OG6
LbrM.25.0680
DNL zinc finger, putative
— Both
LbrM.19.0530
polyprenyl synthase, putative
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— Both
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LbrM.25.0360
translation initiation factor SUI1, putative
— Both
LbrM.12.0300
ornithine decarboxylase, putative
— Both
LbrM.19.1050
Vacuolar protein sorting protein 36 Vps36/EAP
— Both
LbrM.29.2030 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.20.2160 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.27.1830 ⚠
mRNA export factor MEX67
— OG7
LbrM.15.0400 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.30.3660 ⚠
CYC2-like protein, putative
— OG7
LbrM.33.0820 ⚠
G1 cyclin CycE4, putative
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.05.0890 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.24.1950 ⚠
cyclin 11, putative
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.32.0910 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.03.0070 ⚠
Met-10+ like-protein, putative
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.