LbrM.25.0970

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147257 OG7: OG7_0000011 29 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 29 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.2320
hypothetical protein, unknown function
— OG6
LbrM.12.0300
ornithine decarboxylase, putative
— OG6
LbrM.25.0360
translation initiation factor SUI1, putative
— OG6
LbrM.15.0090
ATP-dependent protease ATPase subunit HslU1,
— OG6
LbrM.21.1750
NIMA-related kinase, putative
— OG6
LbrM.34.2220
ATP-dependent RNA helicase-like protein
— OG6
LbrM.35.4280
hypothetical protein, conserved
— OG6
LbrM.29.2190
leucine-rich repeat-containing protein
— OG6
LbrM.30.3650
hypothetical protein, conserved
— OG6
LbrM.35.2650
hypothetical protein, conserved
— OG6
LbrM.35.5860
adenylyl cyclase-associated protein, putative
— OG6
LbrM.29.0070
tryptophanyl-tRNA synthetase, putative
— OG6
LbrM.29.1320
Hsp70 protein/TPR repeat, putative
— OG6
LbrM.27.2130
small nuclear ribonucleoprotein protein, puta
— OG6
LbrM.14.1240
EAP30/Vps36 family, putative
— OG6
LbrM.15.0700
hypothetical protein, conserved
— OG6
LbrM.26.0760
Regulator of chromosome condensation (RCC1) r
— OG6
LbrM.33.2840
metallo-peptidase, Clan MF, Family M17
— OG6
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
LbrM.02.0360
Soluble NSF attachment protein, SNAP, putativ
— OG6
LbrM.11.0970
eukaryotic release factor 3, putative
— OG6
LbrM.14.0420
Protein of unknown function (DUF1253), putati
— OG6
LbrM.03.0180
hypothetical protein
— OG6
LbrM.15.1010
E1-like ubiquitin-activating enzyme, putative
— OG6
LbrM.09.0230
ATP-dependent protease ATPase subunit HslU2
— OG6
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG6
LbrM.11.0800
pyruvate phosphate dikinase, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.