LbrM.11.0400

aminopeptidase, putative, metallo-peptidase, Clan MF, Family M17
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_142599 OG7: OG7_0003405 284 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 284 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— +9 more Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— +9 more Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— +9 more Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— +9 more Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— +9 more Both
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— +3 more Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LbrM.30.0640 ⚠
hypothetical protein, conserved
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.30.0880 ⚠
hypothetical protein, conserved
— Both
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— +2 more Both
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— Both
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— +2 more Both
LbrM.04.0490 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
LbrM.20.5380 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.35.4280 ⚠
hypothetical protein, conserved
— +2 more Both
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.14.0460 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LbrM.15.1160 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LbrM.25.1690 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LbrM.27.1480 ⚠
hypothetical protein, unknown function
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.20.2160 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LbrM.21.0900 ⚠
methionyl-tRNA synthetase, putative
— OG7
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG7
LbrM.30.0780 ⚠
nuclear movement protein, putative, NUDC-like
— OG7
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.07.0840 ⚠
6-phosphofructo-2-kinase-like protein
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.