LbrM.14.0460

N-terminal conserved domain of Nudc./CS domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102007 OG7: OG7_0004626 113 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 113 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— Both
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LbrM.20.5310 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
LbrM.30.3340 ⚠
UV excision repair RAD23-like protein
— Both
LbrM.18.0020 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LbrM.25.1690 ⚠
eukaryotic translation initiation factor 3 su
— Both
LbrM.18.0110 ⚠
alpha glucosidase II subunit, putative
— Both
LbrM.35.5390 ⚠
VHS domain containing protein, putative
— Both
LbrM.22.1120 ⚠
translation initiation factor IF-2, putative
— Both
LbrM.34.0420 ⚠
hypothetical protein, conserved
— Both
LbrM.35.2410 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.29.2090 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LbrM.35.0120 ⚠
stress-inducible protein STI1 homolog
— OG6
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.20.5870 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LbrM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LbrM.22.1440 ⚠
alanyl-tRNA synthetase, putative
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— Both
LbrM.05.0790 ⚠
hypothetical protein, conserved
— Both
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LbrM.35.4280 ⚠
hypothetical protein, conserved
— Both
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.32.4220 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— Both
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.18.1210 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LbrM.24.1540 ⚠
translation initiation factor IF-2, putative
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.31.2160 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG7
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG7
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG7
LbrM.33.0350 ⚠
heat shock protein 83-1
— OG7
LbrM.17.1240 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.28.0340 ⚠
rrp44p homologue, putative
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— OG7
LbrM.33.1320 ⚠
hypothetical protein, conserved
— Both
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.