LbrM.35.0560

dihydrouridine synthase domain protein-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102617 OG7: OG7_0002064 216 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 216 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.3480 ⚠
DNA ligase I, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.34.2860 ⚠
pentatricopeptide repeat domain containing pr
— OG7
LbrM.22.0140 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0020 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
LbrM.28.1320 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2550 ⚠
formate--tetrahydrofolate ligase
— OG7
LbrM.26.1310 ⚠
Cupin-like domain containing protein, putativ
— OG7
LbrM.34.4530 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.1190 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LbrM.03.0510 ⚠
kinase-like protein
— OG7
LbrM.15.1110 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0930 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.18.0110 ⚠
alpha glucosidase II subunit, putative
— OG7
LbrM.31.3350 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.4340 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.33.1670 ⚠
protein kinase
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.16.0400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.20.5310 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
LbrM.31.2940 ⚠
calreticulin, putative
— OG7
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— OG7
LbrM.18.0740 ⚠
HEAT repeats, putative
— OG7
LbrM.23.0660 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.35.6390 ⚠
rab-like GTPase activating protein, putative
— OG7
LbrM.28.1990 ⚠
Replication factor A protein 1
— OG7
LbrM.28.2200 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6380 ⚠
disgorgin, putative
— OG7
LbrM.27.1020 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.30.2810 ⚠
GTPase activator-like protein
— OG7
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG7
LbrM.22.0290 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0710 ⚠
histidyl-tRNA synthetase, putative
— OG7
LbrM.30.1920 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.20.5870 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LbrM.03.0650 ⚠
TatD related DNase, putative
— OG7
LbrM.13.1010 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.