LbrM.13.1010

Thiamin pyrophosphokinase, vitamin B1 binding domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_151510 OG7: OG7_0006221 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.3180 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
LbrM.03.0510
kinase-like protein
— Both
LbrM.06.0030
WD domain, G-beta repeat, putative
— Both
LbrM.03.0670
Ubiquitin-like domain containing protein, put
— Both
LbrM.02.0390
casein kinase II, alpha chain, putative
— OG6
LbrM.03.0650
TatD related DNase, putative
— Both
LbrM.10.0700 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.12.0080 ⚠
ribonuclease mar1
— OG7
LbrM.08.0350 ⚠
Isochorismatase family, putative
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— Both
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.30.2230 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.20.3130 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LbrM.11.0080 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LbrM.26.2000 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4880 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.29.0520 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LbrM.11.0620 ⚠
tubulin-tyrsoine ligase-like protein (fragmen
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.16.0390 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.27.2700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.30.3480
DNA ligase I, putative
— Both
LbrM.31.2280 ⚠
succinyl-diaminopimelate desuccinylase-like p
— Both
LbrM.21.1180 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LbrM.15.1110
hypothetical protein, conserved
— Both
LbrM.30.0600
N-acetyltransferase B complex (NatB) non cata
— Both
LbrM.33.3330
tyrosyl-DNA phosphodiesterase, putative
— Both
LbrM.30.1920
C2H2 type zinc-finger (2 copies), putative
— Both
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.28.2200
hypothetical protein, conserved
— Both
LbrM.31.2100 ⚠
peptidase m20/m25/m40 family-like protein
— Both
LbrM.26.2010 ⚠
hypothetical protein, unknown function
— Both
LbrM.31.2120 ⚠
peptidase m20/m25/m40 family-like protein
— Both
LbrM.33.2100 ⚠
peptidase M20/M25/M40, putative
— Both
LbrM.31.2160 ⚠
dihydrouridine synthase (Dus), putative
— Both
LbrM.28.1990
Replication factor A protein 1
— Both
LbrM.22.1020 ⚠
Beta-lactamase superfamily domain containing
— Both
LbrM.22.1030 ⚠
Beta-lactamase superfamily domain containing
— Both
LbrM.33.1880 ⚠
cytosolic nonspecific dipeptidase, putative
— Both
LbrM.27.0930
WD domain, G-beta repeat, putative
— Both
LbrM.20.4970 ⚠
tubulin-tyrosine ligase, putative
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.10.0690 ⚠
zinc binding dehydrogenase-like protein
— Both
LbrM.08.0360 ⚠
mitochondrial associated ribonuclease, putati
— Both
LbrM.07.0100
pitrilysin-like metalloprotease, metallo-pept
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.