LbrM.17.0330

dihydrouridine synthase (Dus), putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101202 OG7: OG7_0002064 222 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 222 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.3480 ⚠
DNA ligase I, putative
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LbrM.27.2700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.20.4970 ⚠
tubulin-tyrosine ligase, putative
— OG7
LbrM.16.0390 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.11.0620 ⚠
tubulin-tyrsoine ligase-like protein (fragmen
— OG7
LbrM.29.0520 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LbrM.34.4880 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.11.0080 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LbrM.08.0350 ⚠
Isochorismatase family, putative
— OG7
LbrM.30.2230 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.12.0080 ⚠
ribonuclease mar1
— OG7
LbrM.32.3180 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.08.0360 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.30.3070 ⚠
homoserine kinase
— OG7
LbrM.16.0560 ⚠
aspartate carbamoyltransferase, putative
— OG7
LbrM.05.0720 ⚠
Vta1 like, putative
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.25.1640 ⚠
elongation factor 2-like protein
— OG7
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— OG7
LbrM.20.4000 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LbrM.33.1880 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.35.4270 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.20.2300 ⚠
methyltransferase-like protein
— OG7
LbrM.31.2100 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.33.0210 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.31.2120 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LbrM.26.2000 ⚠
hypothetical protein, conserved
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.2750 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LbrM.26.2010 ⚠
hypothetical protein, unknown function
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.