LbrM.05.0200

50S ribosome-binding GTPase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101986 OG7: OG7_0001608 244 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 244 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.16.0400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.10.1250 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.12.0080 ⚠
ribonuclease mar1
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.4270 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.27.1830 ⚠
mRNA export factor MEX67
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.33.0820 ⚠
G1 cyclin CycE4, putative
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.05.0770 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.05.0890 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.24.1950 ⚠
cyclin 11, putative
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.15.0400 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.09.1260 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LbrM.18.1600 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LbrM.29.2030 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.20.2160 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.32.0910 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.31.1770 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0530 ⚠
hypothetical protein, conserved
— Both
LbrM.07.0710 ⚠
eukaryotic translation initiation factor 3 su
— Both
LbrM.02.0390
casein kinase II, alpha chain, putative
— OG6
LbrM.04.0740 ⚠
60S ribosomal protein L10, putative
— Both
LbrM.04.0950 ⚠
60S ribosomal protein L10, putative
— Both
LbrM.27.1110 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.1380 ⚠
hypothetical protein
— OG7
LbrM.22.1350 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0310 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.22.1360 ⚠
Mitochondrial glycoprotein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.