LbrM.04.0290

RNA pseudouridylate synthase-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_185520 OG7: OG7_0001865 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LbrM.30.1590 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LbrM.34.4530 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.5120 ⚠
cyclophilin 15, putative
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.30.0880 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1820 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3060 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.31.1710 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.2250 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— OG7
LbrM.27.1830 ⚠
mRNA export factor MEX67
— OG7
LbrM.20.6130 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.1630 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.35.6540 ⚠
flagellum transition zone component, putative
— OG7
LbrM.14.1240 ⚠
EAP30/Vps36 family, putative
— OG7
LbrM.18.0730 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.33.1670 ⚠
protein kinase
— OG7
LbrM.20.4940 ⚠
conserved protein, unknown function
— OG7
LbrM.05.0890 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.06.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2720 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0490 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.0960 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LbrM.19.0530 ⚠
polyprenyl synthase, putative
— OG7
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.17.1560 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.24.1960 ⚠
cyclin 10
— OG7
LbrM.30.3660 ⚠
CYC2-like protein, putative
— OG7
LbrM.33.0820 ⚠
G1 cyclin CycE4, putative
— OG7
LbrM.29.2130 ⚠
cdc2-related kinase 10, putative
— OG7
LbrM.24.1950 ⚠
cyclin 11, putative
— OG7
LbrM.32.0910 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.25.0680 ⚠
DNL zinc finger, putative
— OG7
LbrM.11.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.20.1180 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.1320 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LbrM.19.1060 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0550 ⚠
hypothetical protein, conserved
— OG7
LbrM.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG7
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— OG7
LbrM.03.0070 ⚠
Met-10+ like-protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.