LbrM.19.1060

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_109594 OG7: OG7_0013700 26 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 26 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.31.1710
hypothetical protein, conserved
— Both
LbrM.26.1180 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— OG7
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.11.0900
hypothetical protein, conserved
— Both
LbrM.18.0730
PA26 p53-induced protein (sestrin), putative
— Both
LbrM.23.1880
Surp module, putative
— Both
LbrM.15.0400 ⚠
RNA pseudouridylate synthase, putative
— Both
LbrM.20.5120
cyclophilin 15, putative
— Both
LbrM.30.0880
hypothetical protein, conserved
— Both
LbrM.10.0330 ⚠
protein transport protein SEC23, putative
— Both
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— Both
LbrM.26.2250
hypothetical protein, conserved
— Both
LbrM.20.6130 ⚠
hypothetical protein, conserved
— Both
LbrM.20.4940 ⚠
conserved protein, unknown function
— Both
LbrM.17.0840
phosphatidylinositol kinase
— Both
LbrM.28.1180
hypothetical protein, conserved
— Both
LbrM.07.0890 ⚠
hypothetical protein, unknown function
— Both
LbrM.07.0910 ⚠
hypothetical protein, conserved
— Both
LbrM.07.0920.B ⚠
hypothetical protein, conserved (fragment)
— Both
LbrM.20.0430 ⚠
hypothetical protein, unknown function
— Both
LbrM.20.0440 ⚠
hypothetical protein, unknown function
— Both
LbrM.07.0920.A ⚠
hypothetical protein, conserved (fragment)
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.