LbrM.18.0730

PA26 p53-induced protein (sestrin), putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_141922 OG7: OG7_0006056 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.5580 ⚠
pumilio protein, putative, RNA-binding regula
— OG7
LbrM.06.0050 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LbrM.21.1990 ⚠
pumillio protein 3, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.12.0400 ⚠
pumillio protein 4, putative
— OG7
LbrM.20.5610 ⚠
RNA-binding regulatory protein, putative, pum
— OG7
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.21.1510 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.17.0040 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.32.2360 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.12.0300
ornithine decarboxylase, putative
— Both
LbrM.11.0900
hypothetical protein, conserved
— Both
LbrM.34.2220
ATP-dependent RNA helicase-like protein
— OG6
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.19.1060
hypothetical protein, conserved
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.23.1630 ⚠
RING-H2 zinc finger, putative
— Both
LbrM.09.0340 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.26.1180 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.4610 ⚠
ubiquitin protein ligase, putative
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.35.3150 ⚠
hypothetical protein, conserved, predicted zi
— OG7
LbrM.33.1360 ⚠
pumilio protein 6, putative
— Both
LbrM.20.3590 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.27.1300 ⚠
RING-H2 zinc finger, putative
— OG7
LbrM.35.0090 ⚠
PUF1, putative
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.22.0060 ⚠
transcription factor-like protein
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— Both
LbrM.19.0530
polyprenyl synthase, putative
— Both
LbrM.18.1450 ⚠
pumilio protein, putative, pumilio protein 2,
— Both
LbrM.20.4940 ⚠
conserved protein, unknown function
— Both
LbrM.17.0840
phosphatidylinositol kinase
— Both
LbrM.29.1330
hypothetical protein, unknown function
— Both
LbrM.32.1190 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.