LbrM.35.4610

ubiquitin protein ligase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478893 OG7: OG7_0002947 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.4770 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.26.0760 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.28.2200 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1990 ⚠
Replication factor A protein 1
— OG7
LbrM.27.1020 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.19.1330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.16.0400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.20.4000 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LbrM.15.1050 ⚠
glutamate dehydrogenase
— OG7
LbrM.20.2300 ⚠
methyltransferase-like protein
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0580 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LbrM.23.1880 ⚠
Surp module, putative
— OG7
LbrM.18.0730 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LbrM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LbrM.11.0720 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LbrM.18.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1320 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.5170 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.3110 ⚠
RNA-binding protein, putative
— OG7
LbrM.34.0910 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.3170 ⚠
Peroxin 19
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.05.0770 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.22.1360 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.26.0450 ⚠
nucleotide binding protein-like protein
— OG7
LbrM.21.0720 ⚠
nucleotide-binding protein, putative
— OG7
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.30.1090 ⚠
p22 protein precursor, putative
— OG7
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.