LbrM.22.0060

transcription factor-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_103027 OG7: OG7_0005137 124 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 124 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.07.0260 ⚠
protein kinase, putative
— OG7
LbrM.09.0810 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.1250 ⚠
WW domain containing protein, putative
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.22.0770 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0300 ⚠
ornithine decarboxylase, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.29.1330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.32.0820 ⚠
Outer row dynein-assembly protein 7
— OG7
LbrM.28.2700 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.31.0480 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.30.0880 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.30.2110 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.26.2280 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.1140 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.0530 ⚠
polyprenyl synthase, putative
— OG7
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.17.1560 ⚠
zinc-finger protein ZPR1, putative
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.25.2410 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.18.0730 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.