LbrM.10.0191

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_105476 OG7: OG7_0010325 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.1490 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.22.0060 ⚠
transcription factor-like protein
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.10.0820 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0500 ⚠
Leucine Rich repeats (2 copies)/Leucine rich
— OG7
LbrM.21.0240 ⚠
CHAT domain containing protein, putative
— OG7
LbrM.24.0660 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.09.1350 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— OG7
LbrM.21.1960 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.23.0520 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
LbrM.17.0380 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.04.0620 ⚠
DENN (AEX-3) domain containing protein, putat
— OG7
LbrM.07.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1490 ⚠
hypothetical protein, unknown function
— OG7
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.09.1150 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0450 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LbrM.16.1190 ⚠
hypothetical protein, conserved
— OG7
LbrM.02.0640 ⚠
Nop14-like family, putative
— OG7
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.02.0360 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.03.0590 ⚠
DEAD/DEAH box helicase, putative
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.28.2080 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LbrM.07.0990 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
LbrM.21.0530 ⚠
vacuolar sorting-associated-like protein
— OG7
LbrM.11.0720 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LbrM.02.0150 ⚠
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.35.1470 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.2430 ⚠
ARM-like helical domain-containing protein
— OG7
LbrM.34.3110 ⚠
RNA-binding protein, putative
— OG7
LbrM.35.2690 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.