LbrM.18.1100

5-oxoprolinase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100892 OG7: OG7_0005437 121 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 121 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.31.0410 ⚠
CRAL/TRIO domain containing protein, putative
— Both
LbrM.21.0530
vacuolar sorting-associated-like protein
— Both
LbrM.33.3020
translation initiation factor IF-2, putative
— Both
LbrM.27.0370
hypothetical protein, conserved
— Both
LbrM.19.1820 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LbrM.23.0520
5'-AMP-activated protein kinase subunit beta,
— Both
LbrM.31.1700
hypothetical protein, unknown function
— Both
LbrM.24.2100
tubulin folding cofactor D, putative
— Both
LbrM.17.0790 ⚠
GMP reductase
— OG6
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.34.2670
hypothetical protein, conserved
— Both
LbrM.22.0060 ⚠
transcription factor-like protein
— Both
LbrM.27.1490
hypothetical protein, unknown function
— Both
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LbrM.24.0500
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LbrM.30.0640
hypothetical protein, conserved
— Both
LbrM.33.2150
hypothetical protein, conserved
— Both
LbrM.28.2080
p21-C-terminal region-binding protein, putati
— Both
LbrM.26.1490 ⚠
farnesyltransferase beta subunit
— Both
LbrM.24.0660 ⚠
PPPDE putative peptidase domain containing pr
— Both
LbrM.34.1630
casein kinase II, putative
— OG6
LbrM.35.3080
hypothetical protein, conserved
— Both
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— Both
LbrM.34.2980
hypothetical protein, conserved
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.18.1140 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.20.3130 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.34.2571 ⚠
ankyrin repeat protein, putative
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.18.1200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.0420 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.13.0680 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LbrM.21.0400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LbrM.34.5250 ⚠
ribosome-interacting GTPase 2, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.