LbrM.17.0790

GMP reductase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100534 OG7: OG7_0002928 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.2500 ⚠
ATP synthase subunit beta, mitochondrial, put
— OG6
LbrM.02.0150 ⚠
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG6
LbrM.25.1230 ⚠
hypothetical protein, conserved
— OG6
LbrM.07.0610 ⚠
hypothetical protein, conserved
— OG6
LbrM.18.1310 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LbrM.32.3080 ⚠
prefoldin subunit, putative
— OG6
LbrM.27.1150 ⚠
cysteine desulfurase, putative
— Both
LbrM.11.0720 ⚠
Short C-terminal domain/PUB domain containing
— OG6
LbrM.25.2510 ⚠
ATP synthase subunit beta, mitochondrial, put
— OG6
LbrM.30.2950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
LbrM.26.0030 ⚠
brix domain containing-like protein
— Both
LbrM.27.0390 ⚠
Nucleolar protein 111, putative
— Both
LbrM.31.2990 ⚠
acetoin dehydrogenase e3 component-like prote
— OG6
LbrM.11.0370 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG6
LbrM.16.0600 ⚠
carbamoyl-phosphate synthase, putative
— OG6
LbrM.30.0700 ⚠
ribosome biogenesis regulatory protein (RRS1)
— Both
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG6
LbrM.16.1450 ⚠
EMG1/NEP1 methyltransferase, putative
— Both
LbrM.34.0090 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— OG6
LbrM.25.1150 ⚠
ATP synthase subunit beta, mitochondrial, put
— OG6
LbrM.31.0230 ⚠
dihydrolipoamide dehydrogenase
— OG6
LbrM.34.1190 ⚠
hypothetical protein, conserved
— Both
LbrM.34.1730 ⚠
Eukaryotic rRNA processing protein EBP2, puta
— Both
LbrM.11.0690 ⚠
hypothetical protein, conserved
— OG6
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG6
LbrM.03.0810 ⚠
peter pan protein, putative
— Both
LbrM.02.0360 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG6
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— OG6
LbrM.27.0900 ⚠
hypothetical protein, conserved
— Both
LbrM.32.0840 ⚠
nuclear RNA binding domain
— Both
LbrM.27.2430 ⚠
EMG1/NEP1 methyltransferase, putative
— OG7
LbrM.33.3020 ⚠
translation initiation factor IF-2, putative
— OG6
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
LbrM.27.0920 ⚠
hypothetical protein, conserved
— Both
LbrM.20.5830 ⚠
ribosome biogenesis protein, putative
— Both
LbrM.25.1180 ⚠
hypothetical protein, conserved
— Both
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG6
LbrM.34.3110 ⚠
RNA-binding protein, putative
— OG6
LbrM.31.2430 ⚠
ARM-like helical domain-containing protein
— OG6
LbrM.35.1470 ⚠
hypothetical protein, conserved
— OG6
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG6
LbrM.26.0850 ⚠
hypothetical protein, conserved
— OG6
LbrM.29.1790 ⚠
MORN repeat, putative
— OG6
LbrM.35.1510 ⚠
hypothetical protein, conserved
— OG6
LbrM.30.1800 ⚠
microtubule associated protein xmap215
— OG6
LbrM.29.2330 ⚠
aspartyl aminopeptidase, putative
— OG6
LbrM.31.0410 ⚠
CRAL/TRIO domain containing protein, putative
— OG6
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG6
LbrM.23.0520 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG6
LbrM.31.1700 ⚠
hypothetical protein, unknown function
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.