LbrM.34.0090

2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101601 OG7: OG7_0003147 23 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 23 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.0600
carbamoyl-phosphate synthase, putative
— Both
LbrM.35.7250 ⚠
Bromodomain factor 1
— OG7
LbrM.35.3590 ⚠
Bromodomain, putative
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.29.2220 ⚠
Aminopeptidase M1, putative
— OG7
LbrM.31.2980 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LbrM.17.0790 ⚠
GMP reductase
— OG6
LbrM.19.1820 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LbrM.31.0230 ⚠
dihydrolipoamide dehydrogenase
— Both
LbrM.05.0180
dihydrolipoamide branched chain transacylase,
— Both
LbrM.31.3570 ⚠
methylcrotonoyl-coa carboxylase biotinylated
— Both
LbrM.35.3320
ATP synthase, putative
— Both
LbrM.35.2580
tyrosine aminotransferase
— Both
LbrM.31.2990 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LbrM.11.0370
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LbrM.21.1810
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
LbrM.01.0080 ⚠
carboxylase, putative
— OG6
LbrM.03.0210
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LbrM.06.0830
dihydrofolate reductase-thymidylate synthase
— Both
LbrM.35.3200 ⚠
bromodomain factor 2 protein, putative
— Both
LbrM.13.0080 ⚠
metallo-peptidase, Clan MA(E) Family M32
— Both
LbrM.33.2810 ⚠
metallo-peptidase, Clan MA(E) Family M32
— Both
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.