LbrM.03.0210

delta-1-pyrroline-5-carboxylate dehydrogenase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102275 OG7: OG7_0000710 38 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 38 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.4150 ⚠
S-adenosylhomocysteine hydrolase
— Both
LbrM.23.0370
(H+)-ATPase G subunit, putative
— Both
LbrM.15.1080 ⚠
Peroxiredoxin PRX1A
— Both
LbrM.28.2630
Vacuolar proton pump subunit B, putative
— Both
LbrM.15.1100 ⚠
tryparedoxin peroxidase
— Both
LbrM.11.0800
pyruvate phosphate dikinase, putative
— Both
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— +1 more Both
LbrM.21.1580
ATP synthase, putative
— Both
LbrM.11.0370
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LbrM.35.3320
ATP synthase, putative
— Both
LbrM.34.0690
vacuolar ATP synthase subunit d, putative
— Both
LbrM.23.1970
cytochrome c oxidase subunit V
— Both
LbrM.23.0050 ⚠
Peroxiredoxin PRX1M
— Both
LbrM.34.0090
2-oxoisovalerate dehydrogenase beta subunit,
— Both
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— +2 more Both
LbrM.22.0530
Uncharacterised protein family UPF0066, putat
— Both
LbrM.12.0480
vacuolar ATP synthase subunit, putative
— Both
LbrM.21.0310
hexokinase, putative
— Both
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.30.3120
valyl-tRNA synthetase, putative
— Both
LbrM.34.3170
Peroxin 19
— Both
LbrM.09.0850 ⚠
oligopeptidase b
— Both
LbrM.20.4450 ⚠
deoxyhypusine synthase, putative
— Both
LbrM.20.0300 ⚠
deoxyhypusine synthase, putative
— Both
LbrM.34.0390
hypothetical protein, conserved
— Both
LbrM.35.4070
glycyl tRNA synthetase, putative
— Both
LbrM.34.0890
hypothetical protein, conserved
— Both
LbrM.31.3470 ⚠
metallopeptidase, putative
— Both
LbrM.31.3520 ⚠
metallo-peptidase, Clan ME, Family M16
— Both
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— Both
LbrM.13.0900
leucyl-tRNA synthetase, putative
— Both
LbrM.30.3460
T-complex protein 11, putative
— Both
LbrM.29.2540
serine/threonine-protein kinase, putative
— OG6
LbrM.35.4140 ⚠
S-adenosylhomocysteine hydrolase
— Both
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +2 more Both
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— +1 more Both
LbrM.20.3260
vacuolar ATP synthase catalytic subunit A, pu
— Both
LbrM.31.3340
acetyl-CoA carboxylase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.