LbrM.33.2210

phosphoribosyl transferase, putative, phosphoribosylpyrophosphate synthetase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100356 OG7: OG7_0002319 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.31.3340 ⚠
acetyl-CoA carboxylase
— +6 more Both
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +4 more Both
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— +6 more Both
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— +5 more Both
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— OG7
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.32.2890 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.26.1100 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.20.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.18.0920 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.25.1240 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.28.1620 ⚠
Cell division control protein 48, putative
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.23.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.14.0550 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.33.0940 ⚠
histone deacetylase, putative
— OG7
LbrM.13.0320 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.10.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.1720 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.16.0030 ⚠
AAA domain containing protein, putative
— OG7
LbrM.20.1390 ⚠
Nucleoporin NUP225
— OG7
LbrM.10.0130 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2350 ⚠
protein kinase, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.05.0860 ⚠
CPSF A subunit region, putative
— OG7
LbrM.17.0940 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.02.0170 ⚠
RNA helicase, putative (fragment)
— OG7
LbrM.25.0290 ⚠
RNA-binding protein, putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.30.2390 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.1310 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.1740 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.15.0710 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0840 ⚠
histone deacetylase, putative
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.05.0410 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LbrM.21.1570 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LbrM.04.0170 ⚠
exosome complex exonuclease RRP40, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.