LbrM.20.2350

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102026 OG7: OG7_0007248 156 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 156 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1400
hypothetical protein, conserved
— Both
LbrM.19.0980 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LbrM.19.0080 ⚠
proteasome alpha 7 subunit, putative
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LbrM.20.1740
Glycosyl hydrolase family 65 central catalyti
— Both
LbrM.20.3930
coatomer alpha subunit, putative
— Both
LbrM.35.5490
glycosyl hydrolase, putative
— Both
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— Both
LbrM.35.5980
hypothetical protein, conserved
— Both
LbrM.20.3720
GRIP domain containing protein, putative
— Both
LbrM.35.5510 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
LbrM.20.3040
hypothetical protein, conserved
— Both
LbrM.20.3740
hypothetical protein, conserved
— Both
LbrM.35.2430
hypothetical protein, conserved
— Both
LbrM.34.2190
hypothetical protein, conserved
— Both
LbrM.34.2430
hypothetical protein, conserved
— Both
LbrM.35.2480
Gamma-tubulin complex component 3-like protei
— Both
LbrM.35.4200
hypothetical protein, unknown function
— Both
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.35.3380 ⚠
tubulin binding cofactor c, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.13.1520 ⚠
chaperonin TCP20, putative
— +3 more OG7
LbrM.10.0900
hypothetical protein, conserved
— OG7
LbrM.24.2370 ⚠
cullin-like protein-like protein
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.1750 ⚠
proteasome subunit alpha type-1, putative
— OG7
LbrM.12.0040 ⚠
proteasome beta-1 subunit, putative
— OG7
LbrM.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LbrM.34.3820 ⚠
proteasome beta 2 subunit, putative
— OG7
LbrM.21.2010 ⚠
proteasome alpha 2 subunit, putative
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.