LbrM.20.3720

GRIP domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147115 OG7: OG7_0043222 243 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 243 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.35.5510 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
LbrM.35.7120 ⚠
beta adaptin, putative
— Both
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— Both
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.11.0080 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LbrM.30.2230 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.32.3220 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LbrM.24.0920 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LbrM.34.4870 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LbrM.33.2980 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LbrM.32.3180 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LbrM.05.0320 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LbrM.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LbrM.28.2580 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LbrM.07.0840 ⚠
6-phosphofructo-2-kinase-like protein
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.03.0700 ⚠
6-phosphofructo-2-kinase 1
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LbrM.35.0720 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LbrM.09.0640 ⚠
ubiquitin-fusion protein
— OG7
LbrM.31.2130 ⚠
ubiquitin-fusion protein
— OG7
LbrM.14.1440 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LbrM.31.2110 ⚠
ubiquitin-fusion protein
— OG7
LbrM.31.2290 ⚠
ubiquitin-fusion protein
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LbrM.35.5200
2OG-Fe(II) oxygenase superfamily, putative
— Both
LbrM.34.3380
acyl transferase-like protein, putative
— Both
LbrM.35.5980
hypothetical protein, conserved
— Both
LbrM.26.1830 ⚠
hypothetical protein, conserved
— Both
LbrM.10.1320 ⚠
hypothetical protein, conserved
— Both
LbrM.30.1400
hypothetical protein, conserved
— Both
LbrM.32.0200
Flagellum attachment zone protein 9
— Both
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LbrM.16.0390 ⚠
tubulin tyrosine ligase, putative
— Both
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.34.2190
hypothetical protein, conserved
— Both
LbrM.26.0740
hypothetical protein, conserved
— Both
LbrM.31.1440
Protein of unknown function (DUF3638)/Protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.