LbrM.34.2360

cysteine peptidase, Clan CA, family C19, putative, ubiquitin hydrolase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_136424 OG7: OG7_0001214 222 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 222 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.0910 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.20.3720 ⚠
GRIP domain containing protein, putative
— OG7
LbrM.31.2780 ⚠
adrenodoxin-like protein, ferredoxin, 2fe-2s-
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.20.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.20.3740 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.24.1070 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LbrM.32.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2920 ⚠
glyoxalase I
— OG7
LbrM.20.1680 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0960 ⚠
adenylate kinase, putative
— OG7
LbrM.21.1450 ⚠
adenylate kinase, putative
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.26.1070 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
LbrM.30.1400 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.31.2850 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LbrM.18.0590 ⚠
tubulin cofactor C domain-containing protein
— OG7
LbrM.19.0980 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.28.1520 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.20.3040 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LbrM.32.1560 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LbrM.22.1110 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0480 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG7
LbrM.08.0840 ⚠
histone deacetylase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.32.0960 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LbrM.32.1850 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
LbrM.10.0130 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0900 ⚠
DNA polymerase theta
— OG7
LbrM.20.1290 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
LbrM.07.1000 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.1260 ⚠
coronin, putative
— OG7
LbrM.35.5980 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3380 ⚠
tubulin binding cofactor c, putative
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.