LbrM.29.0150

DNA-directed RNA polymerase II subunit 3, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101363 OG7: OG7_0003550 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.2250 ⚠
DNA-directed RNA polymerase-like protein
— Both
LbrM.30.1400 ⚠
hypothetical protein, conserved
— Both
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— Both
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
LbrM.25.2130 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +1 more Both
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— +1 more Both
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LbrM.20.2350 ⚠
hypothetical protein, conserved
— Both
LbrM.27.1690 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LbrM.21.1450 ⚠
adenylate kinase, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.04.0960 ⚠
adenylate kinase, putative
— OG7
LbrM.24.1070 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.11.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.23.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.0030 ⚠
AAA domain containing protein, putative
— OG7
LbrM.33.2350 ⚠
protein kinase, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.33.1310 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.34.2190 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.2480 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
LbrM.18.0880 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LbrM.12.0040 ⚠
proteasome beta-1 subunit, putative
— OG7
LbrM.34.3820 ⚠
proteasome beta 2 subunit, putative
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.32.1270 ⚠
histone H2A, putative
— OG7
LbrM.21.1140 ⚠
histone H2A
— OG7
LbrM.21.1150 ⚠
histone H2A, putative
— OG7
LbrM.29.1820 ⚠
histone H2A, putative
— OG7
LbrM.32.1260 ⚠
histone H2A, putative
— OG7
LbrM.29.1810 ⚠
histone H2A, putative
— OG7
LbrM.17.0260 ⚠
histone H2A variant Z
— OG7
LbrM.21.1160 ⚠
histone H2A, putative
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.19.0950 ⚠
histone H3 variant V
— OG7
LbrM.10.0970 ⚠
histone H3
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.