LbrM.31.0270

DNA-directed RNA polymerase II subunit 2, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100190 OG7: OG7_0001821 190 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 190 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.2250 ⚠
DNA-directed RNA polymerase-like protein
— +1 more Both
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LbrM.19.0980 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LbrM.04.0170 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— +1 more OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— +4 more Both
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— +4 more Both
LbrM.31.2990 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LbrM.27.1690 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LbrM.23.1670 ⚠
exosome component CSL4, putative
— OG7
LbrM.31.2980 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LbrM.31.0230 ⚠
dihydrolipoamide dehydrogenase
— OG7
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more OG7
LbrM.34.4880 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.21.1150 ⚠
histone H2A, putative
— OG7
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LbrM.29.1820 ⚠
histone H2A, putative
— OG7
LbrM.32.1260 ⚠
histone H2A, putative
— OG7
LbrM.14.0010 ⚠
ribosomal RNA processing protein 4, putative,
— OG7
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG7
LbrM.29.1810 ⚠
histone H2A, putative
— OG7
LbrM.17.0260 ⚠
histone H2A variant Z
— OG7
LbrM.21.1160 ⚠
histone H2A, putative
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG7
LbrM.22.1540 ⚠
ccr4-not transcription complex subunit
— OG7
LbrM.19.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.2700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.22.1490 ⚠
exosome complex exonuclease RRP45 homolog, pu
— OG7
LbrM.35.5140 ⚠
exosome-associated protein 4, putative
— OG7
LbrM.19.0740 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.35.1570 ⚠
translation elongation factor 1-beta, putativ
— OG7
LbrM.20.0810 ⚠
translation elongation factor 1-beta, putativ
— OG7
LbrM.20.0770 ⚠
elongation factor 1-beta
— OG7
LbrM.20.0750 ⚠
elongation factor 1-beta
— OG7
LbrM.07.0400 ⚠
RAVE protein 1 C terminal, putative
— OG7
LbrM.32.3750 ⚠
exosome-associated protein 2, putative
— OG7
LbrM.30.2230 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.16.0390 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.11.0620 ⚠
tubulin-tyrsoine ligase-like protein (fragmen
— OG7
LbrM.29.0520 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.11.0080 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.