LbrM.14.0010

ribosomal RNA processing protein 4, putative, exosome complex exonuclease, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101400 OG7: OG7_0006776 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.22.1490 ⚠
exosome complex exonuclease RRP45 homolog, pu
— +4 more Both
LbrM.32.3750 ⚠
exosome-associated protein 2, putative
— +4 more Both
LbrM.04.0170
exosome complex exonuclease RRP40, putative
— Both
LbrM.35.3240 ⚠
Ribosomal RNA processing protein 41A
— Both
LbrM.35.5140 ⚠
exosome-associated protein 4, putative
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.26.1160
mitochondrial RNA binding complex 1 subunit,
— Both
LbrM.35.1570 ⚠
translation elongation factor 1-beta, putativ
— Both
LbrM.20.0810 ⚠
translation elongation factor 1-beta, putativ
— Both
LbrM.20.0770 ⚠
elongation factor 1-beta
— Both
LbrM.20.0750 ⚠
elongation factor 1-beta
— Both
LbrM.20.2660
exosome subunit rrp6p homologue, putative
— Both
LbrM.14.0440
mRNA capping enzyme, beta chain, putative
— Both
LbrM.20.2350
hypothetical protein, conserved
— Both
LbrM.23.1670
exosome component CSL4, putative
— Both
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— Both
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.34.4680 ⚠
Hsp70 protein, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.19.0980 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LbrM.26.0500 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0040 ⚠
proteasome beta-1 subunit, putative
— OG7
LbrM.34.3820 ⚠
proteasome beta 2 subunit, putative
— OG7
LbrM.25.1090 ⚠
hypothetical protein, conserved
— Both
LbrM.25.0560
hypothetical protein, conserved
— Both
LbrM.35.2120
hypothetical protein, conserved
— Both
LbrM.35.5030
paraflagellar rod component, putative
— Both
LbrM.01.0590
pre-mRNA processing factor 3 (PRP3)/Protein o
— Both
LbrM.20.1210
hypothetical protein, conserved
— Both
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LbrM.08.0090
adaptor complex protein (AP) 3 delta subunit
— Both
LbrM.09.1380
paraflagellar rod component, putative
— Both
LbrM.25.2130 ⚠
RNA polymerase I second largest subunit, puta
— Both
LbrM.25.1230
hypothetical protein, conserved
— Both
LbrM.09.0120
flagellar pocket cytoskeletal protein bilbo1
— Both
LbrM.24.1480
hypothetical protein, conserved
— Both
LbrM.20.5570
exosome-associated protein 1, putative
— Both
LbrM.27.0890
parallel beta-helix repeat, putative
— Both
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— Both
LbrM.28.3030 ⚠
heat shock protein 70, putative
— OG6
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— Both
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— Both
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— Both
LbrM.30.1400
hypothetical protein, conserved
— Both
LbrM.35.1840 ⚠
proteasome subunit beta type-5, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.