LbrM.01.0590

pre-mRNA processing factor 3 (PRP3)/Protein of unknown function (DUF1115), putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_157627 OG7: OG7_0043643 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— Both
LbrM.16.1300
hypothetical protein, conserved
— Both
LbrM.23.0750
DIM-like protein, putative, spliceosomal U5 s
— Both
LbrM.17.0280
hypothetical protein, conserved
— Both
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— Both
LbrM.33.3460
small nuclear ribonucleoprotein SmD2
— Both
LbrM.16.1690
Putative snoRNA binding domain containing pro
— Both
LbrM.32.2720
hypothetical protein, conserved
— Both
LbrM.34.3940
PRP8 protein homologue, putative, U5 snRNA-as
— Both
LbrM.28.2950 ⚠
receptor for activated C kinase 1
— OG7
LbrM.30.1510 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— OG7
LbrM.27.2130
small nuclear ribonucleoprotein protein, puta
— Both
LbrM.21.1760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LbrM.32.0800 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LbrM.35.0630 ⚠
U2 small nuclear ribonucleoprotein 16.5K, put
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.34.4680 ⚠
Hsp70 protein, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.19.0980 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LbrM.12.0040 ⚠
proteasome beta-1 subunit, putative
— OG7
LbrM.34.3820 ⚠
proteasome beta 2 subunit, putative
— OG7
LbrM.25.1640 ⚠
elongation factor 2-like protein
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.08.0090
adaptor complex protein (AP) 3 delta subunit
— Both
LbrM.28.3170
U5 snRNP-specific 40 kDa protein, putative
— Both
LbrM.32.1630 ⚠
Microtubule-binding protein MIP-T3, putative
— Both
LbrM.32.0760
OSM3-like kinesin, putative
— OG6
LbrM.21.0590
hypothetical protein, conserved
— Both
LbrM.30.0740
pdz domain containing protein, putative
— Both
LbrM.26.0280
hypothetical protein, conserved
— Both
LbrM.21.1340
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LbrM.35.1840 ⚠
proteasome subunit beta type-5, putative
— Both
LbrM.09.1380
paraflagellar rod component, putative
— Both
LbrM.20.1210
hypothetical protein, conserved
— Both
LbrM.14.0010
ribosomal RNA processing protein 4, putative,
— Both
LbrM.25.0560
hypothetical protein, conserved
— Both
LbrM.24.1480
hypothetical protein, conserved
— Both
LbrM.30.1400
hypothetical protein, conserved
— Both
LbrM.20.2350
hypothetical protein, conserved
— Both
LbrM.09.0120
flagellar pocket cytoskeletal protein bilbo1
— Both
LbrM.22.0960
small nuclear ribonucleoprotein, putative, Sm
— Both
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.