LbrM.32.0800

U6 snRNA-associated Sm-like protein LSm4p
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102392 OG7: OG7_0003694 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.22.0960 ⚠
small nuclear ribonucleoprotein, putative, Sm
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.10.0140 ⚠
mitochondrial, DEAD/DEAH box helicase, putati
— OG7
LbrM.27.2690 ⚠
hypothetical protein, conserved, WD-repeat pr
— OG7
LbrM.21.0380 ⚠
U1 small nuclear ribonucleoprotein C, putativ
— OG7
LbrM.35.7370 ⚠
RNA-binding protein 14
— OG7
LbrM.35.0830 ⚠
Protein C21orf2 homolog, putative
— OG7
LbrM.34.3220 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LbrM.25.2300 ⚠
Leucine-rich repeat, putative
— OG7
LbrM.07.0310 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0240 ⚠
U2 small nuclear ribonucleoprotein 40K, putat
— OG7
LbrM.03.0130 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG7
LbrM.34.3010 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG7
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.34.4680 ⚠
Hsp70 protein, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.21.1830 ⚠
arginine N-methyltransferase, type II, putati
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.25.1640 ⚠
elongation factor 2-like protein
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.32.2720 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.28.2950 ⚠
receptor for activated C kinase 1
— OG7
LbrM.28.3170 ⚠
U5 snRNP-specific 40 kDa protein, putative
— OG7
LbrM.30.1510 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.27.2130 ⚠
small nuclear ribonucleoprotein protein, puta
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— +2 more OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— +2 more OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— +2 more OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— +2 more OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— +2 more OG7
LbrM.33.3460 ⚠
small nuclear ribonucleoprotein SmD2
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— +3 more Both
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.01.0590 ⚠
pre-mRNA processing factor 3 (PRP3)/Protein o
— OG7
LbrM.30.2990 ⚠
Lsm5p, putative
— OG7
LbrM.16.1300 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.2270 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LbrM.34.3940 ⚠
PRP8 protein homologue, putative, U5 snRNA-as
— OG7
LbrM.23.0320 ⚠
Checkpoint protein HUS1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.