LbrM.27.2690

hypothetical protein, conserved, WD-repeat protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102145 OG7: OG7_0007160 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.5070
WD domain, G-beta repeat, putative
— Both
LbrM.18.1080
hypothetical protein, unknown function
— Both
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LbrM.09.1270
AAA family ATPase, putative
— Both
LbrM.35.3700 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
LbrM.27.0960 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
LbrM.06.1140
hypothetical protein, conserved
— Both
LbrM.12.0610 ⚠
TPR repeat, putative
— Both
LbrM.21.0380
U1 small nuclear ribonucleoprotein C, putativ
— Both
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.15.0760
hypothetical protein, unknown function
— Both
LbrM.25.2450 ⚠
hypothetical protein, conserved
— Both
LbrM.25.1380 ⚠
hypothetical protein, conserved (fragment)
— Both
LbrM.19.1150 ⚠
Flagellum attachment zone protein 7 (fragment
— OG6
LbrM.19.1160 ⚠
kinesin, putative (fragment)
— OG6
LbrM.19.1000 ⚠
Flagellum attachment zone protein 7
— OG6
LbrM.04.0890
axonemal dynein light chain, putative
— Both
LbrM.22.1540
ccr4-not transcription complex subunit
— Both
LbrM.27.2130
small nuclear ribonucleoprotein protein, puta
— Both
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— Both
LbrM.07.0320
paraflagellar rod protein, putative
— Both
LbrM.19.1410
hypothetical protein, conserved
— Both
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.05.0410 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.35.0630 ⚠
U2 small nuclear ribonucleoprotein 16.5K, put
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
LbrM.32.0800 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.13.1230 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.34.1030 ⚠
zinc finger CCCH domain containing protein 11
— OG7
LbrM.15.0140 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LbrM.34.1010 ⚠
hypothetical protein, unknown function
— OG7
LbrM.15.0150 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LbrM.27.0140 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LbrM.18.0880 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LbrM.05.0420 ⚠
TPR repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.