LbrM.05.0420

TPR repeat, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101939 OG7: OG7_0003813 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.04.0440 ⚠
anaphase promoting complex, subunit 10-like p
— +2 more Both
LbrM.12.0610 ⚠
TPR repeat, putative
— Both
LbrM.30.0800 ⚠
CDC16, putative
— +2 more Both
LbrM.06.1140 ⚠
hypothetical protein, conserved
— Both
LbrM.24.0940 ⚠
hypothetical protein, conserved
— +2 more Both
LbrM.30.1940 ⚠
cyclosome subunit-like protein
— +2 more Both
LbrM.29.1260 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.0760 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.05.0410 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.21.1960 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1290 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.23.0020 ⚠
hypothetical protein, conserved
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.03.0280 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LbrM.21.1570 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LbrM.03.0980 ⚠
hypothetical protein
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.15.0760 ⚠
hypothetical protein, unknown function
— OG7
LbrM.22.1540 ⚠
ccr4-not transcription complex subunit
— OG7
LbrM.20.1420 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— OG7
LbrM.21.0040 ⚠
ring-box protein 1, putative
— OG7
LbrM.24.1670 ⚠
ring-box protein, putative
— OG7
LbrM.16.0640 ⚠
RING-H2 zinc finger, putative
— OG7
LbrM.21.1330 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.3440 ⚠
Flagellar Member 7
— OG7
LbrM.04.0890 ⚠
axonemal dynein light chain, putative
— OG7
LbrM.09.1040 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.35.1120 ⚠
intraflagellar transport protein 122, putativ
— OG7
LbrM.20.5460 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LbrM.13.1230 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.27.2690 ⚠
hypothetical protein, conserved, WD-repeat pr
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.32.0320 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0740 ⚠
pdz domain containing protein, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.