LbrM.34.2290

poly(A)-specific ribonuclease PARN, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_128943 OG7: OG7_0005534 199 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 199 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— OG7
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— OG7
LbrM.11.0170 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0820 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0630 ⚠
U2 small nuclear ribonucleoprotein 16.5K, put
— OG7
LbrM.32.0800 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LbrM.20.3470 ⚠
small nuclear ribonucleoprotein sm d3
— OG7
LbrM.34.1300 ⚠
mitochondrial processing peptidase, beta subu
— OG7
LbrM.21.0240 ⚠
CHAT domain containing protein, putative
— OG7
LbrM.13.0480 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LbrM.32.0280 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— OG7
LbrM.20.3910 ⚠
nucleolar protein family a, putative
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.1970 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LbrM.07.0840 ⚠
6-phosphofructo-2-kinase-like protein
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.18.0370 ⚠
ATP12 chaperone protein, putative
— OG7
LbrM.35.2490 ⚠
developmentally regulated GTP-binding protein
— OG7
LbrM.30.0880 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG7
LbrM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LbrM.27.1480 ⚠
hypothetical protein, unknown function
— OG7
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG7
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.27.1560 ⚠
choline kinase, ethanolamine kinase, putative
— OG7
LbrM.34.1330 ⚠
threonyl-tRNA synthetase, putative
— OG7
LbrM.11.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LbrM.26.1830 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.1540 ⚠
otubain cysteine peptidase, Clan CA, family C
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.34.1390 ⚠
choline/ethanolamine kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.