LbrM.01.0030

DNA-damage inducible protein DDI1-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101685 OG7: OG7_0006273 194 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 194 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— +3 more Both
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— +3 more Both
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.18.0610
hypothetical protein, conserved
— Both
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.24.2100
tubulin folding cofactor D, putative
— Both
LbrM.30.0640
hypothetical protein, conserved
— Both
LbrM.13.0750
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.22.0580
guide RNA associated protein, GAP2, putative
— Both
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.30.1350
Zinc finger, C3HC4 type (RING finger), putati
— Both
LbrM.24.1970
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LbrM.34.1330
threonyl-tRNA synthetase, putative
— Both
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.26.1830 ⚠
hypothetical protein, conserved
— Both
LbrM.34.0890
hypothetical protein, conserved
— Both
LbrM.10.0290
exonuclease, putative
— Both
LbrM.31.1600
hypothetical protein, conserved
— OG7
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— +2 more Both
LbrM.35.5680
branch point binding protein, putative
— Both
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LbrM.35.4480
paraflagellar rod component, putative
— OG6
LbrM.18.1380
hypothetical protein, conserved
— Both
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— Both
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.25.1790
hypothetical protein, conserved
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LbrM.35.7120 ⚠
beta adaptin, putative
— Both
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LbrM.35.2630
serine peptidase, Clan SC, Family S9B
— Both
LbrM.33.0330 ⚠
heat shock protein 83-1
— +2 more Both
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— +2 more Both
LbrM.25.1890
Leucine Rich repeats (2 copies), putative
— Both
LbrM.18.0370
ATP12 chaperone protein, putative
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LbrM.12.0270
cysteinyl-tRNA synthetase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.