LbrM.35.4480

paraflagellar rod component, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_110710 OG7: OG7_0002649 132 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 132 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.03.0700 ⚠
6-phosphofructo-2-kinase 1
— Both
LbrM.07.0840 ⚠
6-phosphofructo-2-kinase-like protein
— Both
LbrM.26.0340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LbrM.23.0300
pteridine reductase 1
— OG6
LbrM.33.0830
ATP synthase F1 subunit gamma protein
— OG6
LbrM.19.0570
C-terminal motor kinesin, putative
— OG6
LbrM.21.1810
2-oxoisovalerate dehydrogenase alpha subunit,
— OG6
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG6
LbrM.32.3160
cysteine peptidase, Clan CA, family C19, puta
— OG6
LbrM.20.1490
Zeta toxin, putative
— OG6
LbrM.09.0820
ubiquitin ligase, putative
— OG6
LbrM.04.0490 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.21.1580
ATP synthase, putative
— OG6
LbrM.29.0260
TPR repeat, putative
— OG6
LbrM.35.3320
ATP synthase, putative
— OG6
LbrM.23.0120
GDP-mannose pyrophosphorylase
— OG6
LbrM.08.0230
ubiquitin-activating enzyme-like protein (fra
— OG6
LbrM.32.0280
Histone chaperone Rttp106-like, putative
— OG6
LbrM.18.0610
hypothetical protein, conserved
— OG6
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— OG6
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— OG6
LbrM.18.1380
hypothetical protein, conserved
— OG6
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.08.0470
WD domain, G-beta repeat, putative
— OG6
LbrM.10.0290
exonuclease, putative
— OG6
LbrM.25.1890
Leucine Rich repeats (2 copies), putative
— OG6
LbrM.18.0370
ATP12 chaperone protein, putative
— OG6
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG6
LbrM.12.0270
cysteinyl-tRNA synthetase, putative
— OG6
LbrM.05.0180
dihydrolipoamide branched chain transacylase,
— OG6
LbrM.25.1790
hypothetical protein, conserved
— OG6
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG6
LbrM.35.2630
serine peptidase, Clan SC, Family S9B
— OG6
LbrM.31.3600 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0390 ⚠
Vps51/Vps67, putative
— OG7
LbrM.29.0720 ⚠
bardet-biedl syndrome 7 protein
— OG7
LbrM.30.1550 ⚠
kinesin, putative
— OG7
LbrM.30.0670 ⚠
Bardet-Biedl syndrome 2 protein
— OG7
LbrM.32.3450 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LbrM.32.1390 ⚠
Bardet-Biedl syndrome 9 protein
— OG7
LbrM.30.2340 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.30.3470 ⚠
protein mkt1, putative
— OG7
LbrM.12.0830 ⚠
hypothetical protein, unknown function
— OG7
LbrM.20.5110 ⚠
transmembrane protein, conserved
— OG7
LbrM.34.2330 ⚠
hypothetical protein, unknown function
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.