LbrM.26.0340

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_132778 OG7: OG7_0002306 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LbrM.35.0150 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LbrM.35.4480 ⚠
paraflagellar rod component, putative
— Both
LbrM.33.0560 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.35.4500 ⚠
serine/threonine kinase, putative
— OG7
LbrM.21.1940 ⚠
protein kinase, putative
— OG7
LbrM.33.2670 ⚠
heat shock protein, putative
— OG7
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.35.5510 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LbrM.34.5270 ⚠
isopentenyl-diphosphate delta-isomerase (type
— OG7
LbrM.34.1770 ⚠
protein kinase-like protein
— OG7
LbrM.14.1060 ⚠
protein kinase, putative
— OG7
LbrM.26.0560 ⚠
galactofuranosyltransferase lpg1-like protein
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.21.1070 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.1810 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
LbrM.33.2090 ⚠
dual-specificity protein kinase, putative
— OG7
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.35.3650 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.18.1380 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.0480 ⚠
beta galactofuranosyl glycosyle transferase
— OG7
LbrM.18.1310 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LbrM.15.1160 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LbrM.15.0170 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
LbrM.27.1480 ⚠
hypothetical protein, unknown function
— OG7
LbrM.25.1790 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.29.0550 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.34.0890 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0580 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.25.0010 ⚠
beta galactofuranosyl transferase
— OG7
LbrM.05.0820 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.35.5420 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LbrM.21.1580 ⚠
ATP synthase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0260 ⚠
TPR repeat, putative
— OG7
LbrM.35.3320 ⚠
ATP synthase, putative
— OG7
LbrM.32.0260 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.1210 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.1530 ⚠
G5-interacting protein, putative
— OG7
LbrM.30.2510 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1010 ⚠
oxidoreductase-like protein
— OG7
LbrM.33.3230 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0200 ⚠
PUB domain containing protein, putative
— OG7
LbrM.29.2680 ⚠
Triglyceride lipase, putative
— OG7
LbrM.32.2970 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3250 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.